Hysteroscopy Pictures…..

Cystic Polyp

During menopause, there is an atrophy of the endometrium as a result of the
low hormonal level. In this situation, can be found atrophyc glands mixed with
cystic ones. Endometrial cystic atrophy is an unusual hysteroscopic finding, most often described in postmenopausal women treated with tamoxifen. This is a benign condition and is not related to endometrial hyperplasia, and thus this
condition is not associated with an increased risk of endometrial adenocarcinoma. (Cheung, V. Y. T. (2017). “Endometrial Cystic Atrophy.” J Minim Invasive Gynecol 24(5): 711.)
Tamoxifen is an antineoplastic drug C26H29NO wich competitively inhibits the
binding of estradiol to estrogen receptors on the breast cancer cell. It was
synthesized in 1962 as a contraceptive pill but later became an essential drug for
the treatment of oestrogen-receptor-positive breast cancer. When estrogen enters a cell and binds to an estrogen receptor, activates genes that produce capable of stimulating cell growth. However, in breast cancer cells, when an estrogen receptor is bound to tamoxifen, its properties are altered in such a way that it can no longer activate genes. The result is a decrease in the growth of breast tissue and of breast cancer tissue (Editors of Encyclopaedia Britannica)